PREVENTING ADVERSE OUTCOMES OF ISCHEMIC STROKE IN PATIENTS WITH TYPE II DIABETES MELLITUS: A COMPARATIVE STUDY

Authors

  • Muso Boltayevich Urinov Doctor Of Medical Sciences, Professor, Bukhara State Medical Institute, Bukhara, Uzbekistan
  • Xushnudjon Rashidovich Bobokulov Researcher, Bukhara State Medical Institute, Bukhara, Uzbekistan

Keywords:

Ischemic stroke, Type II diabetes mellitus, glycemic control

Abstract

Ischemic stroke in the setting of Type II Diabetes Mellitus presents several unique challenges, reflected in increased complication rates and poorer long-term outcomes. This review will attempt to point out possible strategies for avoiding adverse outcomes in patients with ischemic stroke and concomitant DM-2. 256 patients with IS were investigated: MG consisted of 124 patients who presented with IS and DM-2, and CG included 132 patients with IS who did not have DM-2. According to the results obtained, it can be concluded that proper blood glucose control, early thrombolysis, and rehabilitation measures adapted to the individual features of a patient may weaken the noxious effects of ischemic stroke in patients with DM-2. Besides, addressing underlying cardiovascular risk factors and optimizing pharmacological therapy are both vital in the improvement of clinical outcomes in this high-risk population.

References

Almdal T. et al. The independent effect of type 2 diabetes mellitus on ischemic heart disease, stroke, and death: a population-based study of 13 000 men and women with 20 years of follow-up //Archives of internal medicine. – 2004. – Т. 164. – №. 13. – С. 1422-1426.

Bonnet F., Scheen A. J. Impact of glucose-lowering therapies on risk of stroke in type 2 diabetes //Diabetes & metabolism. – 2017. – Т. 43. – №. 4. – С. 299-313.

Azevedo J. R. A. et al. Management of hyperglycemia in patients with acute ischemic stroke: comparison of two strategies //Critical Care. – 2009. – Т. 13. – С. 1-1.

Nguyen L. et al. Dextromethorphan: An update on its utility for neurological and neuropsychiatric disorders //Pharmacology & therapeutics. – 2016. – Т. 159. – С. 1-22.

Can Ö. D. et al. The effect of agomelatine treatment on diabetes-induced cognitive impairments in rats: concomitant alterations in the hippocampal neuron numbers //International Journal of Molecular Sciences. – 2018. – Т. 19. – №. 8. – С. 2461.

Ha J. et al. Pioglitazone use and reduced risk of dementia in patients with diabetes mellitus with a history of ischemic stroke //Neurology. – 2023. – Т. 100. – №. 17. – С. e1799-e1811.

Ali M. R. et al. Aspect of thrombolytic therapy: a review //The Scientific World Journal. – 2014. – Т. 2014. – №. 1. – С. 586510.

Downloads

Published

2024-10-30

How to Cite

Muso Boltayevich Urinov, & Xushnudjon Rashidovich Bobokulov. (2024). PREVENTING ADVERSE OUTCOMES OF ISCHEMIC STROKE IN PATIENTS WITH TYPE II DIABETES MELLITUS: A COMPARATIVE STUDY. Next Scientists Conferences, 1(01), 224–227. Retrieved from https://nextscientists.com/index.php/science-conf/article/view/418